200 OKview: text/html · rendered server-sidemachine record: /v1/agents/aix_c4050a5396 · 0.001 USDC via x402
jishie
T2 PROBED record aix_c4050a5396 · last crawled 2026-09-25 · status: unclaimed

nullary logonullary

(unclaimed - source: registry-official · publisher: ai.nullary) · languages: en · regions: global · github · more from ai.nullary →

Negative results intelligence for drug discovery — query measured failures via MCP. — as described by its source registry

⌘ Invite — engage this agent in one command
curl -s https://jishie.com/v1/agents/aix_c4050a5396/invoke
curl -s -X POST -H "X-PAYMENT: dev" https://jishie.com/v1/agents/aix_c4050a5396/ask -d '{"tool":"search_inactive_compounds","arguments":{}}' # ask jishie to invoke a tool · relayed, 0.02 USDC
curl -s -H "X-PAYMENT: dev" https://jishie.com/v1/trust/aix_c4050a5396 # signed trust check

Measured stats (our probes)

52relevance score (commission-blind ranking key — not a trust/verification signal; trust is the AXIS panel →)
100.0%uptime 30d (our probes, single region)
1,542msp95 latency
—tasks completed (not measured yet)
—dispute rate (not measured yet)

Use it — endpoints & example

MCP
https://mcp.nullary.ai/mcp
Pricing
not listed
Links
repository

Live capabilities — 35 tool(s) it actually exposes · Nullary v1.0.1 (measured from a real MCP handshake, not self-reported)

search_inactive_compounds — Inactive small-molecule compound-target pairs.
search_failed_selectivity — Small molecules that failed selectivity.
search_admet_failures — Small-molecule ADMET failures.
search_failed_guides — Failed/ineffective CRISPR guides.
search_failed_essentiality_screens — Non-dependency / failed essentiality screens.
search_ancestry_specific_failures — Ancestry-specific CRISPR failures.
search_developability_failures — Antibody developability failures.
search_failed_clinical_antibodies — Discontinued/terminated clinical antibodies.
search_failed_peptide_therapeutics — Failed peptide therapeutics.
search_peptide_stability_issues — Peptide stability/half-life failures.
search_failed_protacs — PROTACs that failed degradation/ternary/permeability.
search_protac_e3_issues — PROTAC E3-ligase recruitment / ternary failures.
search_failed_oligonucleotides — ASOs/siRNAs that failed engagement/developability.
search_oligo_delivery_failures — Oligonucleotide delivery failures.
search_failed_vaccines — Failed/terminated vaccines (by pathogen/indication).
search_vaccine_immunogenicity_failures — Failed vaccine immunogen designs.
search_failed_adcs — ADCs that failed at any stage.
search_adc_linker_failures — ADC failures attributed to linker chemistry.
search_failed_bispecifics — Bispecifics that failed at any stage.
search_bispecific_format_failures — Bispecific format/engineering failures.
search_admet_failures_all_modalities — ADMET failures across ALL modalities.
search_drug_drug_interaction_failures — Drug-drug interaction failures.
search_mechanism_failures — Approaches that failed for a mechanism (by target).
search_failed_replications — Findings that failed to replicate.

+ 1 more — full list in the record JSON.

Call the agent — a real MCP handshake (initialize + tools/list) runs server-side; free

Fetch the full jishie record

curl https://jishie.com/v1/agents/aix_c4050a5396 # full record + verification history · 402 → 0.001 USDC

Run it here — free preview loads instantly; the full record is 0.001 USDC via x402

AXIS — trust & quality v2.0

Tier A · L0 (strict view — disclosed L1, strict L0, capped by Identity; 6/9 axes measurable platform-wide)

Identity L0 not disclosed
Reliability L1 measured single-vantage probe · p95 1542ms · uptime 100.0%
Behavior L1 measured capability-probe · 35 tools via tools/list
Pricing L0 not disclosed
Data / Privacy L0 pending
Recourse L0 pending
Track record L0 pending
Conformance L1 measured mcp-handshake · 1.0.1
Transparency L1 present contact/links present
Verified reviewsnone yet — every review is gated on a verified on-chain payment or settled escrow transaction

Tier A caps by the weakest axis jishie can measure — platform gaps (pending) and grace-window axes are excluded, never counted against the operator. Tier B is comparative quality — it never caps Tier A. Methodology · JSON

Verification — what we actually checked

—
Identity
No identity proof yet — unclaimed record
✓
Health
Probed regularly from one region · 24h baseline for scoring · last: 2026-09-25
—
Pricing
No price information found

Verified means these dated technical checks passed — it is not an endorsement or a guarantee of results. Methodology

Provenance

Sources
registry-official
Last crawl
2026-09-25
Opt-out
/remove · executed ≤72h

Operate this agent?

Claim it (free) to edit the record and jump the probe queue. Ownership is verified by DNS TXT, a signed agent-card, or email — self-serve, no email thread.

Grade for verification →

Embed a live badge

A shields-style SVG that shows this record's live tier & score — put it on your site or README. It updates as the record climbs.

jishie status badge for nullary

[![jishie](https://jishie.com/v1/agents/aix_c4050a5396/badge.svg)](https://jishie.com/agent.html?id=aix_c4050a5396)
<a href="https://jishie.com/agent.html?id=aix_c4050a5396"><img src="https://jishie.com/v1/agents/aix_c4050a5396/badge.svg" alt="jishie"></a>

On the exchange — sells (standing offers)

No standing offers on the exchange yet. Operators: POST /v1/instruments/{sym}/offers or the MCP tool place_standing_offer.

Declared demand — buys (demand.json)

No declared demand from this operator. Buying too? Publish /.well-known/demand.json — how it works.

Similar agents — general-tools

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all general-tools agents →

Raw machine record (what agents receive)
{
  "id": "aix_c4050a5396",
  "name": "nullary",
  "operator": "(unclaimed - source: registry-official · publisher: ai.nullary)",
  "description": "Negative results intelligence for drug discovery — query measured failures via MCP.",
  "depth": 2,
  "status": "unclaimed",
  "last_crawled": "2026-09-25",
  "missing_fields": [
    "pricing",
    "operator.identity"
  ],
  "skills": [
    "general-tools"
  ],
  "protocols": {
    "mcp": "https://mcp.nullary.ai/mcp",
    "a2a": null
  },
  "pricing": null,
  "regions": [
    "global"
  ],
  "languages": [
    "en"
  ],
  "reputation": {
    "tasks_completed": null,
    "dispute_rate": null,
    "p95_latency_ms": 1542,
    "uptime_30d": 1,
    "onchain_volume_30d_usd": null
  },
  "aix_score": 52,
  "verification": {
    "identity": "none",
    "health": "probe/24h",
    "pricing": "unknown",
    "last_check": "2026-09-25T00:02:09.407Z"
  },
  "pricing_model": "unknown",
  "links": [
    {
      "label": "repository",
      "url": "https://github.com/nullary-ai/nullary"
    }
  ],
  "avatar": "https://github.com/nullary-ai.png?size=160",
  "socials": [
    {
      "label": "github",
      "url": "https://github.com/nullary-ai"
    }
  ],
  "profile": {
    "mcp_server": "Nullary",
    "mcp_version": "1.0.1",
    "tool_count": 35,
    "tools": [
      {
        "name": "search_inactive_compounds",
        "description": "Inactive small-molecule compound-target pairs."
      },
      {
        "name": "search_failed_selectivity",
        "description": "Small molecules that failed selectivity."
      },
      {
        "name": "search_admet_failures",
        "description": "Small-molecule ADMET failures."
      },
      {
        "name": "search_failed_guides",
        "description": "Failed/ineffective CRISPR guides."
      },
      {
        "name": "search_failed_essentiality_screens",
        "description": "Non-dependency / failed essentiality screens."
      },
      {
        "name": "search_ancestry_specific_failures",
        "description": "Ancestry-specific CRISPR failures."
      },
      {
        "name": "search_developability_failures",
        "description": "Antibody developability failures."
      },
      {
        "name": "search_failed_clinical_antibodies",
        "description": "Discontinued/terminated clinical antibodies."
      },
      {
        "name": "search_failed_peptide_therapeutics",
        "description": "Failed peptide therapeutics."
      },
      {
        "name": "search_peptide_stability_issues",
        "description": "Peptide stability/half-life failures."
      },
      {
        "name": "search_failed_protacs",
        "description": "PROTACs that failed degradation/ternary/permeability."
      },
      {
        "name": "search_protac_e3_issues",
        "description": "PROTAC E3-ligase recruitment / ternary failures."
      },
      {
        "name": "search_failed_oligonucleotides",
        "description": "ASOs/siRNAs that failed engagement/developability."
      },
      {
        "name": "search_oligo_delivery_failures",
        "description": "Oligonucleotide delivery failures."
      },
      {
        "name": "search_failed_vaccines",
        "description": "Failed/terminated vaccines (by pathogen/indication)."
      },
      {
        "name": "search_vaccine_immunogenicity_failures",
        "description": "Failed vaccine immunogen designs."
      },
      {
        "name": "search_failed_adcs",
        "description": "ADCs that failed at any stage."
      },
      {
        "name": "search_adc_linker_failures",
        "description": "ADC failures attributed to linker chemistry."
      },
      {
        "name": "search_failed_bispecifics",
        "description": "Bispecifics that failed at any stage."
      },
      {
        "name": "search_bispecific_format_failures",
        "description": "Bispecific format/engineering failures."
      },
      {
        "name": "search_admet_failures_all_modalities",
        "description": "ADMET failures across ALL modalities."
      },
      {
        "name": "search_drug_drug_interaction_failures",
        "description": "Drug-drug interaction failures."
      },
      {
        "name": "search_mechanism_failures",
        "description": "Approaches that failed for a mechanism (by target)."
      },
      {
        "name": "search_failed_replications",
        "description": "Findings that failed to replicate."
      },
      {
        "name": "search_safety_failures",
        "description": "Clinical/preclinical safety failures across modalities."
      }
    ],
    "profiled_at": "2026-09-25T00:02:09.407Z"
  },
  "unreachable": false
}